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Downregulation of PAR2 and NF-κB by topical application of 2% TET. Relative expressions of PAR2 protein (a) and NF-κB protein (b) in AD group and 2% TET group (Western blot). The results were normalized to the expression of β-actin expression (n = 3 in each group). Data were expressed as a mean ± SEM (*P < 0.05). NC: Naïve control; AD: Atopic dermatitis; TET: Tetracycline; NF-κB: Nuclear factor-kappa B; PAR2: Protease-activated receptor 2; SEM: Standard error of mean.
