Table V.

Multivariable Analysis to determine predictors of Eczema at Age 4 Years^†±

	N Eczema/N Total (% with Eczema)	Adjusted Odds ratio[95% CI]	p-value
History of parental eczema	27/96 (28%)	2.2 [1.1–4.3]	0.03
Egg ingestion before age 1 year	54/383 (14%)	0.6 [0.3–1.1]	0.08
Sensitization to egg (age 1 year)	23/58 (40%)	3.9 [1.8–8.7]	<0.001
Sensitization to elm (ages 1,2, and/or 3 years)	18/48 (38%)	2.8 [1.1–7.2]	0.03
Interaction Terms
Dog in home (before age 1; n=184)‡
SPT+ to Dog (ages 1,2, and/or 3)	2/14 (14%)	1.3§	0.8
versus		[0.3–6.8]
SPT− to Dog (ages 1,2, and/or 3)	14/160 (9%)
No Dog in home (before age 1; n=325)
SPT+ to Dog (ages 1,2, and/or 3)	17/30 (57%)	3.9	0.002
versus		[1.6–9.2]
SPT− to Dog (ages 1,2, and/or 3)	38/253 (15%)
Cat in home (before age 1; n=121)‡
SPT+ to Cat (ages 1,2, and/or 3)	7/13 (54%)	13.3§	<0.001
versus		[3.1–57.9]
SPT− to Cat (ages 1,2, and/or 3)	10/95 (11%)
No Cat in home (before age 1; n=353)
SPT+ to Cat (ages 1,2, and/or 3)	16/49 (33%)	1.1	0.8
versus		[0.5–2.7]
SPT− to Cat (ages 1,2, and/or 3)	39/304 (13%)

^†Total cohort size was 636 children at age 4 years; 90 children (16%) met criteria for eczema based parental report

^‡16 (9%) children with eczema owned dogs; 17 (14%) owned cats; based on home visit

^§Represents adjusted odds ratio for eczema based on the interaction between pet ownership and skin prick test (SPT)

^±Table II represents covariates that remained in the final model after backward elimination with an alpha cut-off of 0.15.