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. Author manuscript; available in PMC: 2016 Jun 16.

Published in final edited form as: Hum Hered. 2014 Jul 8;78(1):47–58. doi: 10.1159/000363411

Table 5.

Significant associations of common SNPs with diabetes related phenotypes

Gene	SNP	HbA1c	FPG	2hOGTT	FPI	HOMA IR	Matsuda index	Disposition index	Diabetes	Prediabetes
ADCY5	rs11708067	0.0031^*	0.0306						0.0473	0.0447
CDKN2A/B	rs10811661			0.0169^*			0.0090^*			0.0115^*
CRY2	rs11605924	0.0163
FTO	rs8050136				0.0210	0.0284
FTO	rs3751812				0.0085	0.0088
FTO	rs9939609				0.0298	0.0409			0.0149
FTO	rs17818902			0.0338^*
G6PC2	rs560887		0.0049		0.0213	0.0115
GCK	rs4607517	4.0 × 10⁻⁵	0.0004	0.0147						0.0037
GLIS3	rs7034200
IGF1	rs35767									0.0229^*
JAZF1	rs864745
MADD	rs7944584		0.0020
MTNR1B	rs10830963		0.0109					0.0105
PROX1	rs340874	0.0053^*
SLC2A2	rs11920090				0.0138	0.0177	0.0245
TCF7L2	rs7903146				0.0443
TCF7L2	rs12243326		0.0474
TCF7L2	rs12255372		0.0450
THADA	rs7578597							0.0276		0.0358^*

Both corrected (p ≤ 0.0015; in bold) and uncorrected (p ≤ 0.05) p values for multiple testing by trait are shown, p values are nominal and from MGA;

^*

p values are from QTDT because of the presence of population stratification.