. Author manuscript; available in PMC: 2017 May 1.

Published in final edited form as: J Immunotoxicol. 2015 Nov 19;13(3):403–416. doi: 10.3109/1547691X.2015.1111960

Table 4.

Effects of 24 h, 48 h and 6 days exposures to HBCD on IL -1 β secretion from highly purified human NK cells.

24 h	Interleukin 1 beta secreted in pg/mL (mean±S.D.)

[HBCD] μM	KB179	KB181	KB182
0	295±7	275±19	933±33
0.05	279±8	829±31^*	1385±63^*
0.1	348±10^*	620±54^*	1536±67^*
0.25	353±10^*	827±28^*	1446±39^*
0.5	389±8^*	623±52^*	1752±63^*
1	416±13^*	860±98^*	2006±26^*
2.5	426±17^*	6356±76^*	1911±34^*
5	213±21^*	5914±76^*	1358±70^*

48 h	Interleukin 1 beta secreted in pg/mL (mean±S.D.)

[HBCD] μM	KB179	KB181	KB182
0	222±13	959±20	984±86
0.05	360±7^*	1728±77^*	2673±10^*
0.1	364±15^*	2231±59^*	2403±49^*
0.25	428±1^*	1854±60^*	3158±72^*
0.5	420±16^*	2111±95^*	2870±109^*
1	475±11^*	4139±56^*	3100±116^*
2.5	449±18^*	10087±397^*	3420±150^*
5	112±1^*	8731±169^*	1045±73^*

6d	Interleukin 1 beta secreted in pg/mL (mean±S.D.)

[HBCD] μM	KB179	KB181	KB182
0	245±45	2509±128	972±45^*
0.05	610±46^*	2415±71	2465±75^*
0.1	646±27^*	3106±134^*	2003±32^*
0.25	443±83^*	2932±84^*	2058±115^*
0.5	423±34^*	3119±116^*	1833±102^*
1	385±66^*	4534±157^*	2007±18^*
2.5	245±45	6614±405^*	1317±76^*
5	156±3	7542±169^*	1186±38^*

Values are mean±S.D. of triplicate determinations.

Indicates a significant change in secretion compared to control cells (cells treated with vehicle alone), p<0.05