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CK14 labels the bottom three to four cell layer thick strata of epithelial cells, whereas involucrin labels the upper five to six layers of cells. Most CK14 expressing cells do not express involucrin. Very occasional cells coexpress CK14 and involucrin (arrow). Scale bars 10 μm. CK = cytokeratin. [Color figure can be viewed in the online issue, which is available at www.laryngoscope.com.]
