Table 5. Erythrocyte, leukocyte and platelet counts and characteristics after treatment with andiroba oil.
| Andiroba oil (mg/kg/day) | ||||
|---|---|---|---|---|
| Parameters | Negative control | 500 | 1000 | 2000 |
| Erythrocytes | ||||
| RBC x 106/μL | 8.80 ± 0.35 | 8.93 ± 0.40 | 9.04 ± 0.29 | 8.57 ± 0.38 |
| HGB (g/dL) | 12.48 ± 0.45 | 12.50 ± 0.41 | 12.65 ± 0.40 | 12.07 ± 0.42 |
| HCT (%) | 32.23 ± 1.22 | 32.58 ± 1.12 | 32.75 ± 0.91 | 31.38 ± 1.05 |
| MCV (fL) | 36.7 ± 0.69 | 36.5 ± 0.72 | 36.2 ± 0.53 | 36.6 ± 0.64 |
| MCH (pg) | 14.2 ± 0.3 | 14.0 ± 0.5 | 14.0 ± 0.2 | 14.1 ± 0.2 |
| MCHC (g/dL) | 38.7 ± 0.41 | 38.4 ± 0.56 | 38.6 ± 0.48 | 38.5 ± 0.31 |
| RDW (%) | 13.57 ± 0.69 | 14.37 ± 1.13 | 14.17 ± 0.83 | 13.62 ± 0.78 |
| Leukocytes | ||||
| WBC x 103/μL | 2.23 ± 1.12 | 2.32 ± 1.16 | 2.53 ± 1.13 | 1.78 ± 0.75 |
| W-SCR (%) | 71.57 ± 9.24 | 71.45 ± 16.52 | 75.95 ± 10.58 | 76.38 ± 9.21 |
| W-MCR (%) | 27.78 ± 8.41 | 28.00 ± 16.16 | 23.57 ± 10.27 | 22.38 ± 7.28 |
| W-LCR (%) | 0.65 ± 1.02 | 0.38 ± 0.52 | 0.48 ± 0.68 | 1.23 ± 2.88 |
| Platelets | ||||
| PLT x 103/mL | 1371 ± 207 | 1479 ± 248 | 1442 ± 231 | 1340 ± 295 |
| PDW (fL) | 7.02 ± 0.48 | 7.00 ± 0.20 | 6.80 ± 0.11 | 7.00 ± 0.17 |
| MPV (fL) | 6.53 ± 0.48 | 6.48 ± 0.31 | 6.42 ± 0.13 | 6.38 ± 0.19 |
| P-LCR (%) | 7.28 ± 3.27 | 7.04 ± 2.04 | 7.28 ± 1.05 | 6.10 ± 1.75 |
HCT – hematocrit, HGB – hemoglobin, MCH – mean corpuscular hemoglobin, MCHC – mean corpuscular hemoglobin concentration, MCV – mean corpuscular volume, MPV – mean platelet volume, PDW – platelet distribution width, PLT – platelets, P-LCR – platelet large cell ratio, RBC – red blood cells (erythrocytes), RDW – red cell distribution width, WBC – white blood cells (leukocytes), W-LCR – eosinophils, W-MCR – neutrophils + monocytes, W-SCR – lymphocytes, fL – femtoliter, g/dL – g/deciliter, pg – picogram. The values represent the mean ± SD and were analyzed by ANOVA. There were no significant differences between the responses to andiroba oil and the negative control, or among the doses of oil tested.