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. 2016 Apr-Jun;39(2):270–278. doi: 10.1590/1678-4685-GMB-2015-0184

Table 2. The average cell viability (%) of HTC cells exposed to L3 and LNO3 for 24, 48 and 72 hours obtained from cytotoxicity assay (MTT). The cell viability percentage was calculated from absorbance values obtained from cytotoxicity assay. The positive control was doxorubicin (10μg/mL).

Treatments Times of Exposure
[μg/mL] 24 hours 48 hours 72 hours
CTRL 100 ± 3.158 100 ± 2.580 100 ± 0.7976
DXR 10 59.48 ± 4.214a * 26.00 ± 1.620a * 10.34 ± 0.9262a *
L3 50 111.3 ± 3.698 102.5 ± 6.041 98.00 ± 2.527
100 106.7 ± 1.764 94.06 ± 5.536 97.13 ± 1.815
250 106.6 ± 1.809 93.64 ± 3.592 94.83 ± 1.719
500 99.82 ± 5.079 89.76 ± 4.653 92.07 ± 1.780a *
LNO3 50 97.73 ± 2.795 98.39 ± 2.674 97.62 ± 1.793
100 94.41 ± 4.886 92.61 ± 0.6698 99.39 ± 2.865
250 86.05 ± 5.918 84.25 ± 0.4903 87.38 ± 2.212a *
500 80.06 ± 6.226 67.52 ± 2.168a * 78.23 ± 0.4306a * b *

CTRL: Control; DXR: Doxorubicin;

a

Statistically significant compared to control;

b

Statistically significant compared to L3 at the same concentration.

*

p ≤ 0.05.