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Pimozide reduces EpCAM and β-catenin protein levels in EpCAM(+) cells. (A) Representative Western blots showing reduction in EpCAM protein expression in Hep3B and HepG2 cells following PMZ treatment. β-catenin and phosphorylated β-catenin (S675) protein expression is reduced following PMZ treatment in HepG2 cells. (B) Representative Western blot showing reduction of nuclear β-catenin following PMZ treatment in Hep3B cells. Phosphorylated GSK3β abundance is reduced with PMZ treatment.
