Table 1.
Baseline sociodemographic, clinical, and functional characteristics of 220 COPD patients from five European sites
| Baseline characteristics | All patients
|
|---|---|
| n=220 | |
| Age (years), m (SD) | 67 (8) |
| Sex: male, n (%) | 149 (68%) |
| Living alone, n (%) | 108 (49%) |
| Socio-economic status:a low (IV and V), n (%) | 30 (14%) |
| Active worker, n (%) | 26 (12%) |
| Smoking status: current, n (%) | 38 (17%) |
| Pack years, median (P25 to P75) | 47 (31 to 72) |
| Any COPD exacerbation in the previous year, n (%) | 88 (40%) |
| mMRC score, median (P25 to P75) | 2 (1 to 2) |
| Number of chronic diseases (other than COPD), median (P25 to P75) | 2 (1 to 3) |
| Cardiovascular disease,b n (%) | 118 (54%) |
| Diabetes, n (%) | 19 (9%) |
| Musculoskeletal diseases,c n (%) | 48 (22%) |
| Osteoporosis,d n (%) | 23 (10%) |
| Body mass index (kg/m2), m (SD) | 27 (5) |
| Fat free mass index (kg/m2), m (SD) | 18 (3) |
| FEV1 (% predicted), m (SD) | 57 (20) |
| COPD severity stages | |
| I – Mild (FEV1 ≥80%) | 30 (14) |
| II – Moderate (FEV1 <80% and ≥50%) | 101 (46) |
| III – Severe (FEV1 <50% and ≥30%) | 69 (31) |
| IV – Very severe (FEV1 <30%) | 20 (9) |
| RV/TLC (%), m (SD) | 51 (11) |
| Six minutes walking distance test, m (SD) | 423 (130) |
| CAT score (0 to 40), median (P25 to P75) | 14 (8 to 21) |
| Probable anxiety (HADS-A ≥11), n (%) | 23 (10%) |
| Probable depression (HADS-D ≥11), n (%) | 12 (5%) |
Notes:
Socio-economic status was measured through the UK National Statistics Socio-economic classification.
Cardiovascular disease was the presence of doctor-diagnosed diseases in medical records (ICD9 390–459).
Musculoskeletal diseases included connective tissue diseases (ICD9 710–739).
Osteoporosis included osteoporosis (ICD9 733.0) and osteopenia (ICD9 733.90).
Abbreviations: m, mean; SD, standard deviation; P25, 25th percentile; P75, 75th percentile; mMRC, Modified Medical Research Council Dyspnea Scale; FEV1, forced expiratory volume in 1 second; RV/TLC, residual volume to total lung capacity ratio; CAT, COPD assessment test; HADS-A, Hospital Anxiety and Depression Scale-Anxiety; HADS-D, Hospital Anxiety and Depression Scale-Depression; ICD, International Classification of Diseases.