Table 4.
Baseline characteristics of the CORDIOPREV study.
| All patients (n=1002) | Mediterranean Diet group (n=502) | Low-Fat Diet group (n=500) | p-value | |
|---|---|---|---|---|
| Age, years | 59.5 (0.2) | 59.7 (0.4) | 59.5 (0.4) | NS |
| Male/Female, n | 837/165 | 420/82 | 417/83 | NS |
| Metabolic Syndrome, % | 58.0 | 55.6 | 60.4 | NS |
| SBP, mmHg | 138.8 (0.6) | 138.5 (0.9) | 139.0 (0.9) | NS |
| DBP, mmHg | 77.2 (0.3) | 77.2 (0.5) | 77.3 (0.5) | NS |
| Weight, Kg | 85.1 (0.4) | 84.9 (0.6) | 85.4 (0.7) | NS |
| Height, m | 1.7 (0.0) | 1.7 (0.0) | 1.7 (0.0) | NS |
| Waist circumference, cm | 105.1 (0.3) | 104.9 (0.5) | 105.4 (0.5) | NS |
| BMI, kg/m2 | 31.1 (0.1) | 31.0 (0.1) | 31.2 (0.2) | NS |
| Total Cholesterol, mg/dl | 159.0 (1.0) | 159.1 (1.5) | 159.0 (1.3) | NS |
| HDL-c, mg/dl | 42.2 (0.3) | 42.3 (0.5) | 42.1 (0.5) | NS |
| LDL-c, mg/dl | 88.5 (0.8) | 88.9 (1.2) | 88.2 (1.1) | NS |
| APO-A, mg/dl | 129.6 (0.7) | 129.7 (1.0) | 129.5 (0.9) | NS |
| APO-B, mg/dl | 73.6 (0.5) | 73.6 (0.8) | 73.7 (0.8) | NS |
| TG, mg/dl | 135.4 (2.2) | 134.8 (3.1) | 136.0 (3.2) | NS |
| Fasting Plasma Glucose, mg/dl | 113.7 (1.2) | 114.7 (1.8) | 112.8 (1.6) | NS |
| Family history of premature coronary artery disease, % | 14.9 | 14.9 | 14.8 | NS |
| Family history of DM, % | 46.7 | 45.6 | 47.8 | NS |
| Diabetes mellitus, % | 32.3 | 31.9 | 32.8 | NS |
| Hypertension, % | 68.5 | 69.2 | 67.9 | NS |
| Normal systolic function (LVEF ≥50%), % | 94.9 | 94.3 | 95.6 | NS |
| History of myocardial infarction, % | 61.9 | 62.2 | 61.6 | NS |
| History of CABG, % | 3.2 | 3.8 | 2.6 | NS |
| history of PCI, % | 91.5 | 91.2 | 91.8 | NS |
| Current smoker, % | 9.7 | 8.7 | 10.7 | NS |
| Former smoker, % | 64.6 | 63.9 | 65.2 | NS |
| History of stroke or TIA, % | 5.1 | 5.2 | 5.0 | NS |
| History of peripheral vascular disease, % | 2.9 | 3.0 | 2.8 | NS |
| History of prior malignancy, % | 2.6 | 3.6 | 1.6 | 0.04 |
| Baseline medication, % | ||||
| Antiplatelets | 96.6 | 96.9 | 96.4 | NS |
| Statins | 85.6 | 84.9 | 86.4 | NS |
Data are given as Mean (SE) value or percentage of participants unless otherwise specified.
Abbreviations:APO-A, apolipoprotein A1; APO-B, apolipoprotein B; BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); CABG, Coronary artery bypass grafting; DBP, diastolic blood pressure; DM, diabetes mellitus; HDL-C, high-density lipoprotein cholesterol; LDL-c, low-density lipoprotein; LVEF, left ventricular ejection fraction; NS, not significant (p-value>0.05); PCI, percutaneous coronary intervention; SBP, systolic blood pressure; TIA, transient ischemic attack; TG, triglycerides. SI conversion factors: To convert to millimol per liter, multiply by 0.0259 for HDL-C, by 0.0113 for triglycerides, and by 0.0555 for glucose; to convert insulin to picomol per liter, multiply by 6.945.
We used unpaired T-tests for quantitative variables and Chi-Square for categorical.