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Development of cytotoxic and targeted agents for the treatment of colorectal cancer. 1KRAS wide-type patients. CRC: Colorectal cancer; 5-FU: 5-fluorouracil; LV: Leucovorin; IFL: Irinotecan + 5-fluorouracil + leucovorin; FOLFOXIRI: Leucovorin + 5-fluorouracil + oxaliplatin + irinotecan.
