Table 3.
Clinicopathologic feature | n | 5-yr survival rate (%) | P value1 |
Gender | 0.280 | ||
Male | 93 | 44.08 | |
Female | 49 | 38.77 | |
Age (yr) | 0.580 | ||
< 60 | 78 | 41.02 | |
≥ 60 | 64 | 43.75 | |
Tumour size (cm) | 0.000a | ||
< 5 | 79 | 62.02 | |
≥ 5 | 63 | 17.46 | |
Borrmann type | 0.000a | ||
I + II | 33 | 78.78 | |
III + IV | 109 | 31.19 | |
Histology | 0.260 | ||
Adenocarcinoma | 118 | 40.67 | |
Others | 23 | 52.17 | |
Differentiation | 0.000a | ||
High/moderate | 36 | 69.44 | |
Low/undifferentiated | 106 | 33.01 | |
Tumour invasion | 0.000a | ||
T1-2 | 32 | 84.37 | |
T3-4 | 110 | 30.00 | |
Lymph node metastasis | 0.003a | ||
N0-1 | 54 | 57.40 | |
N2-3 | 88 | 32.95 | |
TNM stage | 0.000a | ||
I-II | 33 | 84.84 | |
III-IV | 109 | 29.35 | |
VEGF expression | 0.003a | ||
Negative | 58 | 56.89 | |
Positive | 84 | 32.14 | |
VEGFR2 expression | 0.000a | ||
Negative | 66 | 68.18 | |
Positive | 76 | 19.73 | |
Endocan-MVD | 0.000a | ||
Low | 75 | 64.00 | |
High | 67 | 17.91 |
Log-rank test;
P < 0.05, statistically significant. VEGF: Vascular endothelial growth factor; VEGFR2: VEGF receptor 2; MVD: Microvessel density.