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. 2016 Jun 16;7:915. doi: 10.3389/fmicb.2016.00915

Table 1.

Antifungals used.

Fluconazole Caspofungin Anidulafungin Micafungin Ambisome Voriconazole Other
Episode 1
No. (%) 78 (64.5) 17 (14) 16 (13.2) 8 (6.6) 1 (0.8) 1 (0.8) 0 (0)
Patient ages (mean) 60.3 67.6 61.3 72.9 0.01 40 0 (0)
Route PO/IV IV IV IV IV IV
No. days used (mean) 6.5 4.7 8.9 4.8 8 1 0(0)
Outcome dead (no. (%)) 20 (27.4) 7 (43.75) 8 (57.1) 2 (33.3) 1 (100) 0 (0) 0 (0)

Species specific [No. (%)] Candida albicans 29 (59.2) 10 (20.4) 7 (14.3) 2 (4.1) 1 (2) 0 (0) 0 (0)
C. glabrata 27 (69.2) 2 (5.1) 5 (12.8) 4 (10.3) 0 (0) 1 (2.6) 0 (0)
C. parapsilosis 11 (55) 4 (20) 3 (15) 2 (10) 0 (0) 0 (0) 0 (0)
C. tropicalis 5 (100) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0)
Others 6 (75) 1 (12.5) 1 (12.5) 0 (0) 0 (0) 0 (0) 0 (0)

Episode 2
No. (%) 40 (57.1) 4 (5.7) 16 (22.9) 1 (1.4) 2 (2.9) 1 (1.4) 6 (8.6)
No. days used (mean) 9.7 8.3 8.5 19 16 22 7.7

Episode 3
No. (%) 13 (50) 1 (3.8) 1 (3.8) 1 (3.8) 2 (7.7) 7 (26.9) 1 (3.8)
No. days used (mean) 7.8 19 10.83 2

An episode is defined as a positive blood culture >21 days after the last positive culture or if a new Candida sp. isolated.