Table 1.
Fluconazole | Caspofungin | Anidulafungin | Micafungin | Ambisome | Voriconazole | Other | ||
---|---|---|---|---|---|---|---|---|
Episode∗ 1 | ||||||||
No. (%) | 78 (64.5) | 17 (14) | 16 (13.2) | 8 (6.6) | 1 (0.8) | 1 (0.8) | 0 (0) | |
Patient ages (mean) | 60.3 | 67.6 | 61.3 | 72.9 | 0.01 | 40 | 0 (0) | |
Route | PO/IV | IV | IV | IV | IV | IV | ||
No. days used (mean) | 6.5 | 4.7 | 8.9 | 4.8 | 8 | 1 | 0(0) | |
Outcome dead (no. (%)) | 20 (27.4) | 7 (43.75) | 8 (57.1) | 2 (33.3) | 1 (100) | 0 (0) | 0 (0) | |
Species specific [No. (%)] | Candida albicans | 29 (59.2) | 10 (20.4) | 7 (14.3) | 2 (4.1) | 1 (2) | 0 (0) | 0 (0) |
C. glabrata | 27 (69.2) | 2 (5.1) | 5 (12.8) | 4 (10.3) | 0 (0) | 1 (2.6) | 0 (0) | |
C. parapsilosis | 11 (55) | 4 (20) | 3 (15) | 2 (10) | 0 (0) | 0 (0) | 0 (0) | |
C. tropicalis | 5 (100) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | |
Others | 6 (75) | 1 (12.5) | 1 (12.5) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | |
Episode 2 | ||||||||
No. (%) | 40 (57.1) | 4 (5.7) | 16 (22.9) | 1 (1.4) | 2 (2.9) | 1 (1.4) | 6 (8.6) | |
No. days used (mean) | 9.7 | 8.3 | 8.5 | 19 | 16 | 22 | 7.7 | |
Episode 3 | ||||||||
No. (%) | 13 (50) | 1 (3.8) | 1 (3.8) | 1 (3.8) | 2 (7.7) | 7 (26.9) | 1 (3.8) | |
No. days used (mean) | 7.8 | 19 | 10.83 | 2 | ||||
∗An episode is defined as a positive blood culture >21 days after the last positive culture or if a new Candida sp. isolated.