Table 5.
Cutoff value, sensitivity, specificity, and AUC in classifying MPE and TPE cases
| Group and cutoff | Sensitivity % (95% CI) | Specificity % (95% CI) | AUC (95% CI) | P-value |
|---|---|---|---|---|
| IL-1β, <5.50 pg/mL | 86.4 (65.1–97.1) | 80 (28.4–99.5) | 0.80 (0.62–0.98) | 0.04* |
| IP-10 (CXCL10), <4,005 pg/mL | 100 (84.6–100) | 80 (28.4–99.5) | 0.95 (0.86–1.05) | <0.01* |
| IL-13, <7.94 pg/mL | 86.4 (65.1–97.1) | 80 (28.4–99.5) | 0.86 (0.71–1.02) | 0.01* |
| IFN-γ, <100.5 pg/mL | 100 (84.8–100) | 80 (28.4–99.5) | 0.83 (0.52–1.13) | 0.02* |
| Basic FGF, >2.39 pg/mL | 72.7 (49.8–89.2) | 80 (28.4–99.5) | 0.81 (0.64–0.98) | 0.03* |
Note:
*
P<0.05
Abbreviations: AUC, area under the curve; MPE, malignant pleural effusion; TPE, tuberculous pleural effusion; IL, interleukin; IP-10, interferon-induced protein-10; CXCL10, chemokine (C–X–C motif) ligand 10; IFN, interferon; FGF, fibroblast growth factor; CI, confidence interval.