Table 2.

Frequency of autoantibody against MDM2 and c-Myc in human sera by ELISA.

	Sera	anti-MDM2	p	anti-c-Myc	p	anti-MDM2 or anti-c-Myc	p
Research group	Lung cancer (n = 50)	9 (18.0% )		8 (16.0%)		13 (26.0%)
	NHC (n = 44)	1 (2.3% )	0.018*	1 (2.3% )	0.034*	2 (4.5%)	0.005**
Validation group	Lung cancer (n = 62)	23 (37.1%)		22 (35.5%)		37 (59.7%)
	NHC (n = 43)	1 (2.3%)	0.000**	1 (2.3%)	0.000**	2 (4.7%)	0.000**

^*p < 0.05

^**p < 0.01 (χ²-test or Fisher's exact test)