Table 4.

Univariate and Multivariate analyses of OS/DFS (Cox proportional hazards regression model).

Factors	OS univariate analysis		DFS univariate analysis
	HR(95% CI)	p	HR(95% CI)	p
Pathology	1.271 (0.281–5.740)	0.755	1.416 (0.329–6.182)	0.635
T	0.983 (0.098–9.861)	0.988	1.544(0.159–14.980)	0.708
N	6.523 (0.556–76.475)	0.135	2.468 (0.346–17.617)	0.368
Stage	6.740 (0.673–67.458)	0.104	5.106 (0.527–49.475)	0.159
Grade	2.492 (0.373–16.675)	0.346	0.292 (0.030–2.807)	0.286
History of malignancies	1.787 (0.248–12.856)	0.564	2.484 (0.350–17.641)	0.363
Family Hx of lung cancer	2.026 (0.180–22.743)	0.567	1.074 (0.111–10.355)	0.951
Largest tumor on CT/PET scan (cm)	0.792 (0.111–5.605)	0.817	0.922 (0.129–6.592)	0.935
Chest wall/Mediastinal invasion	7.101 (0.960–52.519)	0.055	11.090 (1.584–79.437)	0.017*
Post-op chemo	2.584 (0.352–18.431)	0.354	2.043 (0.287–14.529)	0.476
Metastasis after surgery	8.770 (0.905–85.020)	0.061	11.920 (1.165–121.938)	0.037*
Serum c-Myc level (high/low)	54.131 (0.002–1414979.961)	0.442	68.224 (0.022–212584.586)	0.304
Serum MDM2 level (high/low)	0.670 (0.087–5.131)	0.700	1.091 (0.153–7.749)	0.931
Factors	OS multivariate analysis		DFS multivariate analysis
	HR(95% CI)	p	HR(95% CI)	p
Stage	5.398 (1.028–28.339)	0.046*	–	–
Chest wall/Mediastinal invasion	–	–	28.261 (2.364–337.872)	0.008**
Metastasis after surgery	–	–	27.377 (1.721–435.490)	0.019*

^*p < 0.05

^**p < 0.01