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. 2016 Feb 18;5(5):e1137417. doi: 10.1080/2162402X.2015.1137417

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© 2016 The Author(s). Published with license by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License http://creativecommons.org/licenses/by-nc/3.0/, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 2. — Dynamic change of thymic output during and after chemotherapy in 54 patients with B cell lymphoma. Thymic output was monitored by measuring CD31⁺ recent thymic emigrants (RTE) (A) counts and single-joint T-cell receptor excision circles (sjTREC) (B) levels in the peripheral blood prior (baseline), during (after three cycles of chemotherapy) and after (0, 3, 6, 9, 12 mo post-chemotherapy) treatment. Both of the CD31⁺ RTE counts and sjTREC levels decreased to the nadir at the end of treatment and recovered within one year of follow-up. Data are shown as mean ± SD. p values were assessed by general linear model analysis for repeated measure data. ^★p < 0.05, versus baseline levels;^#p < 0.001,vs. the nadir at the end of treatment.