Table 2.

The relationships between TLR3, 7 and 8 histoscores compared to clinicopathological variables in esophageal adenocarcinoma.

		TLR3 histoscore n (%)			TLR7 histoscore n (%)			TLR8 histoscore n (%)
Variable	n/N (%)	Weak	Strong	p	Weak	Strong	p	Weak	Strong	p
pT
T1–2	29/94 (31)	5 (29)	24 (31)	0.887	9 (22)	20 (38)	0.100	12 (27)	17 (35)	0.400
T3–4	65/94 (69)	12 (71)	53 (69)		32 (78)	33 (62)		33 (73)	32 (65)
Lymph nodes
Negative	35/94 (37)	7 (41)	28 (36)	0.710	14 (34)	21 (40)	0.586	14 (31)	21 (43)	0.239
Positive	59/94 (63)	10 (59)	49 (64)		27 (66)	32 (60)		31 (69)	28 (57)
Organ metastases
Negative	63/94 (67)	13 (77)	50 (65)	0.360	27 (66)	36 (68)	0.832	33 (73)	30 (61)	0.212
Positive	31/94 (33)	4 (23)	27 (35)		14 (34)	17 (32)		12 (27)	19 (39)
Grade
1	29/93 (31)	2 (12)	27 (36)	0.209	10 (24)	19 (37)	0.385	9 (20)	20 (42)	0.088
2	22/93 (24)	4 (24)	18 (24)		10 (24)	12 (24)		11 (24)	11 (23)
3	42/93 (45)	11 (65)	31 (41)		22 (52)	20 (39)		25 (56)	17 (35)
Stage
I	13/94 (14)	3 (18)	10 (13)	0.895	4 (10)	9 (17)	0.672	4 (9)	9 (18)	0.194
II	37/94 (39)	6 (35)	31 (40)		17 (42)	20 (38)		21 (47)	16 (33)
III	13/94 (14)	3 (18)	10 (13)		7 (17)	6 (11)		8 (18)	5 (10)
IV	31/94 (33)	5 (29)	26 (34)		13 (32)	18 (34)		12 (27)	19 (39)
Tumor resection
Inoperable	28/99 (28)	6 (33)	22 (27)	0.599	11 (26)	17 (30)	0.601	5 (11)	23 (43)	<0.001
Operable	71/99 (72)	12 (67)	59 (73)		32 (74)	39 (70)		41 (89)	30 (57)
Tumor size
Small (<40mm)	38/92 (41)	6 (38)	38 (42)	0.734	13 (33)	25 (48)	0.133	15 (33)	23 (49)	0.129
Large (≥40mm)	54/92 (59)	10 (63)	44 (58)		27 (68)	27 (52)		30 (67)	24 (51)