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. 2015 Oct 29;5(5):e1100793. doi: 10.1080/2162402X.2015.1100793

Figure 1.

Figure 1.

Acceleration of tumor development associated with NOD genetic background. Mice transgenic for the RET oncogene were monitored weekly for the onset of tumors at the eye, the primary site (A) and for local (B) and distant (C) cutaneous (cut.) metastases. The comparison included mice with a B6 background, F1 mice intercrossed with NOD mice, and these F1 mice backcrossed with NOD at the second (F2), third (F3) and tenth (F10) generation. Data are displayed using the Kaplan–Meier representation.