. 2015 Dec 8;31(3):294–301. doi: 10.1007/s12291-015-0533-x

Table 5.

Enzyme profile in blood serum on the basis of duration (months) of using oral contraceptives

Duration (months)	N	Alkaline phosphatase (U/L)		Lactate dehydrogenase (U/L)		Aminotransferases
Duration (months)	N	Alkaline phosphatase (U/L)		Lactate dehydrogenase (U/L)		SGOT (U/L)		SGPT (U/mL)
1–6	62	60.53 ± 5.74*^,a	Y = 68.455 − 1.553X; r = −0.99; p < 0.0010	365.35 ± 33.52*^,a	Y = 344.05 + 2.7780X; r = 0.971; p < 0.0005	24.83 ± 5.78*^,a	Y = 21.680 + 0.55900X; r = 0.985; p < 0.0027	29.54 ± 2.35*^,a	Y = 26.70 + 0.51850X; r = 0.996; p < 0.0004
7–12	79	48.07 ± 8.11*^,b		372.69 ± 41.29*^,a,b		28.15 ± 4.79*^,b		33.11 ± 2.47*^,b
13–18	65	39.81 ± 6.54*^,c		389.55 ± 48.94*^,b		32.83 ± 5.67*^,c		36.47 ± 2.41*^,c
19–24	94	32.22 ± 4.22^d		415.29 ± 49.62^c		34.45 ± 6.63*^,d		38.79 ± 2.05*^,d
Non users	300	87.16 ± 14.76		363.11 ± 26.84		27.93 ± 3.86		26.52 ± 3.28

Duration (months)	N	γ-Glutamyltransferase (U/L)		Serum proteins
Duration (months)	N	γ-Glutamyltransferase (U/L)		Albumin (g/dL)		Globulin (g/dL)
1–6	62	26.51 ± 4.76*^,a	Y = 25.34 + 0.23183X; r = 0.97; p < 0.0007	3.80 ± 0.34*^,a	Y = 4.0750 − 0.0355X; r = −0.97; p < 0.0007	3.51 ± 0.48*^,a	Y = 3.385 + 0.02483X; r = 0.986; p < 0.0002
7–12	79	28.69 ± 5.40*^,a,b,c		3.71 ± 0.30*^,a		3.73 ± 0.44*^,b
13–18	65	29.04 ± 4.6*^,b,c		3.50 ± 0.28*^,b		3.81 ± 0.51*^,b,c
19–24	94	31.03 ± 5.49*^,c		3.16 ± 0.37*^,c		3.98 ± 0.54*^,d
Non users	300	22.84 ± 5.67		4.24 ± 0.36		3.38 ± 0.46

U user, NU non users

* Significant difference between oral contraceptive users and non-users (p < 0.05). Superscript of different alphabets denotes significant difference between different age groups among oral contraceptive users (ANOVA) post hoc Tukey test