. Author manuscript; available in PMC: 2016 Jun 16.

Published in final edited form as: Curr Treat Options Neurol. 2012 Jun;14(3):241–255. doi: 10.1007/s11940-012-0172-y

Table 2.

Treatment of tuberculous meningitis with low probability of drug resistance

Drug	Usual daily dose	Maximum dose	Duration
Isoniazid	5–10 mg/kg	300 mg	6 months
Rifampin	10–20 mg/kg	600 mg	6 months
Pyrazinamide	15–30 mg/kg	2,500 mg	2 months
		OR
Isoniazid	5–10 mg/kg	300 mg	9 months
Rifampin	10–20 mg/kg	600 mg	9 months
Ethambutol	15–25 mg/kg		2 months
		OR
Streptomycin	15 mg/kg	1,000 mg	2 months
Isoniazid	5–10 mg/kg or 15 mg/kg (2× week)	900 mg	8 months
Rifampin	10–20 mg/kg or 10–20 mg/kg (2× week)	600 mg	8 months