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. Author manuscript; available in PMC: 2016 Jun 16.
Published in final edited form as: Ann Neurol. 2011 Aug;70(2):305–322. doi: 10.1002/ana.22408

Table 2. Clinical Characteristics of Reported Cases of PML in Solid Organ Transplantation Recipients (January 1971–July 2010).

Author Last Name (Year of Publication) Sex/Age at Transplantation Underlying Disease Prompting Transplantation Method of Diagnosis Survival from Symptom Onset (mo)a Attempted Treatment
Lung (3)
 1 Ouwens (2000)28 43/M Bronchiectasis CSF PCR 20 Y
 2 Shitrit (2003)29 58/M Idiopathic pulmonary fibrosis Biopsy NP Y
 3 Waggoner (2009)30 38/F Idiopathic pulmonary fibrosis CSF PCR 5.25 Y
Heart (4)
 4 Hall (1988)31 59/M Ischemic cardiomyopathy Autopsy 0.75 N
 5 Flomenbaum (1991)32 49/M Ischemic heart disease, Coronary artery disease Autopsy <1 N
 6 Lewis (1993)33 59/M Ischemic heart disease Biopsy 15 N
 7 McCalmont (2007)34 68/M Idiopathic cardiomyopathy Autopsy 0.5 N
Liver (6)
 8 Worthmann (1994)35 53/F Hepatitis C, cirrhosis Autopsy Asymptomatic N
 9 Bronster (1995)36 51/M Cryptogenic cirrhosis Biopsy 2.25 Y
 10 Boulton-Jones (2001)37 60/F Secondary biliary cirrhosis CSF PCR 22 Y
 11 Koralnik (2004)38 66/M Nephrolithiasis Biopsy 4 N
 12 Lima (2005)39 39/F Hepatitis C, cirrhosis CSF PCR 1.75 Y
 13 Alibert (2006)40 59/F Hepatitis C, cirrhosis CSF PCR <6 Y
Kidney (19)
 14 Manz (1971)4 33/F Minimal glomerular change disease Autopsy 3.5 N
 15 ZuRhein (1974)41 34/M Chronic glomerulonephritis Autopsy 2 N
 16 Legrain (1974)42 19/F Chronic pyelonephritis Autopsy 6 N
 17 McCormick (1976)43 34/M Chronic proliferative glomerulonephritis Autopsy 2.75 N
 18 Selhorst (1978)44 50/F Not provided Biopsy 27+ Y
 19 Egan (1980)46 53/M Chronic glomerulonephritis Autopsy 2.5 N
 20 Ho (1980)47 65/F Radiation nephritis Autopsy 6 N
 21 Reznik (1981)A48 51/M Hypertensive nephropathy Autopsy 13 N
 22 Reznik (1981)B48 45/F Extramembranous glomerulonephrosis Autopsy 38 N
 23 Holzhausen (1984)49 44/M Glomerulonephritis Autopsy 2 N
 24 Saxton (1984)50 28/M Not stated Biopsy 13.5+ Y
 25 Garcia (1985)51 28/M Chronic active glomerulonephritis Biopsy ∼5+ Y
 26 Embrey (1988)52 18/M Obstructive nephropathy, solitary kidney Biopsy NP Y
 27 Táborský (1998)53 66/M Chronic glomerulonephritis CSF PCR 5.25 Y
 28 Berner (1999)53 69/M Chronic pyelonephritis CSF PCR 4 N
 29 Phillips (2004)54 16/M ANCA-associated glomerulonephritis CSF PCR <1.25 N
 30 Crowder (2005)55 47/M Alport syndrome Biopsy 37+ Y
 31 Manfro (2009)56 52/F Chronic pyelonephritis Biopsy 4+ Y
 32 Epker (2009)57 50/M Proliferative glomerulonephritis, diabetes mellitus CSF PCR 6+ Y

n = 32.

a

Case was reported before the time of death (censored at time of reporting; eg, 7+ equals survival last reported at 7 months).

ANCA = antineutrophil cytoplasmic antibody; CSF = cerebrospinal fluid; NP = not provided; PCR = polymerase chain reaction.