Table 4. Clinical Characteristics of Reported Cases of PML in Bone Marrow Transplantation Recipients (January 1971–July 2010).
| Bone Marrow | Author Last Name (Year of Publication) | Sex/Age at Transplantation | Underlying Disease Prompting Transplantation | Method of Diagnosis | Survival from Symptom Onset (mo) | Attempted Treatment |
|---|---|---|---|---|---|---|
| 33 | Mesquita (1992)58 | 47/M | Polymorphic centroblastic lymphoma | Autopsy | 2+ | N |
| 34 | O'shaughnessy (1994)59 | 44/F | Chronic myeloid leukemia | Biopsy | 4 | Y |
| 35 | Seong (1996)60 | 31/F | Chronic myeloid leukemia | Biopsy | NP | NP |
| 36 | Przepoirka (1997)61 | 46/F | Low-grade lymphoma | Biopsy | 12 | Y |
| 37 | Coppo (1999)62 | 38/F | Acute leukemia, hepatitis C | CSF PCR | 3 | Y |
| 38 | Re (1999)63 | 54/F | Mantle cell lymphoma | Biopsy | 11.25 | Y |
| 39 | Owen (1995)64 | 43/M | Chronic myeloid leukemia | MRI | 2 | Y |
| 40 | Goldberg (2002)65 | 34/F | Non-Hodgkin's lymphoma | CSF PCR | 7+ | Y |
| 41 | Goldberg (2002)65 | 42/F | Non-Hodgkin's lymphoma | CSF PCR | 30 | N |
| 42 | Osorio (2002)66 | 60/M | Mantle cell lymphoma | Biopsy | 5 | Y |
| 43 | Buckanovich (2002)67 | 29/F | Hodgkin's lymphoma | MRI | 6.5 | Y |
| 44 | Steurer (2003)68 | 32/M | Diffuse large cell lymphoma | Biopsy | 3 | Y |
| 45 | Gabriel (2007)69 | 45/M | Cutaneous T-cell lymphoma | Autopsy | NP | N |
| 46 | Focosi (2007)70 | 33/F | Acute lymphoblastic leukemia | Biopsy | 11 | Y |
| 47 | Karfan-Dabaja (2007)71 | 51/M | Follicular non-Hodgkin's lymphoma | Biopsy | 2 | Y |
| 48 | Karfan-Dabaja (2007)71 | 41/M | Hodgkin's lymphoma | CSF PCR | 1.25+ | Y |
| 49 | Yasuda (2008)72 | 14/M | Wiskott-Aldrich syndrome | CSF PCR and autopsy | 2.5+ | Y |
| 50 | Sheikh (2009)73 | 38/F | Acute myeloid leukemia | Autopsy | 1.5+ | NP |
| 51 | Chowdhary (2008)74 | 51/M | Non-Hodgkin's lymphoma, myelodysplasia | Biopsy | NP | NP |
| 52 | Pelosini (2008)75 | 30/F | Acute lymphoblastic leukemia | Biopsy | 18 | Y |
| 53 | Fianchi (2010)76 | 63/F | Multiple myeloma | Biopsy | 15 | Y |
| 54 | Tuccori (2010)77 | 45/M | Mantle cell lymphoma | CSF PCR | 7+ | Y |
n = 22.
CSF = cerebrospinal fluid; MRI = magnetic resonance imaging; NP = not provided; PCR = polymerase chain reaction; PML = progressive multifocal leukoencephalopathy.