Table 1.
Characteristic | Antepartum (n = 149) | Delivery (n = 103) | P Value |
---|---|---|---|
Household sociodemographics | |||
Urban/periurban residence, n (%) | 129 (86) | 72 (69) | 0.005* |
House with ≤2 rooms, n (%) | 130 (87) | 85 (82) | 0.78 |
Median adults in house | 2 (2–4) | 2 (2–5) | 0.53 |
Median children in house | 1 (1–2) | 2 (1–2) | 0.01* |
Personal sociodemographics, n (%) | |||
Employed for pay | 29 (19) | 18 (17) | 0.31 |
Education ≤fourth grade | 30 (20) | 39 (37) | 0.03* |
Biomass cooking fuel | 15 (10) | 25 (24) | 0.002* |
Moderate to severe food insecurity | 14 (9) | 11 (10) | 0.68 |
Obstetric history | |||
Gestational age | 26 (22–31) | NA | — |
First prenatal visit, n (%) | 24 (16) | NA | — |
First pregnancy, n (%) | 43 (29) | 39 (38) | 0.11 |
HIV history | |||
Median CD4 | 468 (343–606) | 447 (319–622) | 0.42 |
cART use, n (%) | 68 (45) | 48 (46) | 0.33 |
cART before pregnancy | 26 (18) | 18 (18) | 0.99 |
TB risk factors, n (%) | |||
History of TB | 1 (0.6) | 2 (2) | 0.36 |
History of IPT | 0 (0) | 0 (0) | >0.95 |
Close contact with TB | 12 (8) | 3 (3) | 0.11 |
Contact with MDR-TB | 5 (3) | 0 (0) | 0.25 |
Positive TB symptom screen | 15 (10) | 11 (11) | 0.79 |
Household contact with TB symptoms | 12 (8) | 5 (4) | 0.31 |
Smoker in the house | 31 (20) | 23 (22) | 0.38 |
LTBI results | |||
TST | 0.78 | ||
Positive ≥5 mm, n (%) | 18 (12) | 9 (8) | |
TST+ median induration, mm (IQR) | 16 (13–21) | 13 (12–15) | 0.19 |
Negative, n (%) | 125 (83) | 88 (85) | |
Did not return, n (%) | 6 (4) | 6 (6) | |
QGIT | 0.86 | ||
Positive, n (%) | 42 (28) | 29 (28) | |
QGIT+ median IFN-γ, IU/ml (IQR) | 3.22 (1.26–9.79) | 1.84 (0.84–4.63) | 0.11 |
Negative, n (%) | 103 (69) | 70 (67) | |
Indeterminate, n (%) | 4 (2) | 4 (3) |
Definition of abbreviations: cART = combination antiretroviral therapy; IPT = isoniazid preventive therapy; IQR = interquartile range; LTBI = latent tuberculosis infection; MDR-TB = multidrug-resistant tuberculosis; NA = not applicable; QGIT = QuantiFERON TB Gold In-Tube test; TB = tuberculosis; TST = tuberculin skin test.
Statistically significant.