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. 2016 Jun 15;193(12):1421–1428. doi: 10.1164/rccm.201508-1595OC

Table 1.

Participant Characteristics and LTBI Test Results by Time Point of Screening

Characteristic Antepartum (n = 149) Delivery (n = 103) P Value
Household sociodemographics      
 Urban/periurban residence, n (%) 129 (86) 72 (69) 0.005*
 House with ≤2 rooms, n (%) 130 (87) 85 (82) 0.78
 Median adults in house 2 (2–4) 2 (2–5) 0.53
 Median children in house 1 (1–2) 2 (1–2) 0.01*
Personal sociodemographics, n (%)      
 Employed for pay 29 (19) 18 (17) 0.31
 Education ≤fourth grade 30 (20) 39 (37) 0.03*
 Biomass cooking fuel 15 (10) 25 (24) 0.002*
 Moderate to severe food insecurity 14 (9) 11 (10) 0.68
Obstetric history      
 Gestational age 26 (22–31) NA
  First prenatal visit, n (%) 24 (16) NA
  First pregnancy, n (%) 43 (29) 39 (38) 0.11
HIV history      
 Median CD4 468 (343–606) 447 (319–622) 0.42
 cART use, n (%) 68 (45) 48 (46) 0.33
  cART before pregnancy 26 (18) 18 (18) 0.99
TB risk factors, n (%)      
 History of TB 1 (0.6) 2 (2) 0.36
 History of IPT 0 (0) 0 (0) >0.95
 Close contact with TB 12 (8) 3 (3) 0.11
 Contact with MDR-TB 5 (3) 0 (0) 0.25
 Positive TB symptom screen 15 (10) 11 (11) 0.79
 Household contact with TB symptoms 12 (8) 5 (4) 0.31
 Smoker in the house 31 (20) 23 (22) 0.38
LTBI results      
 TST     0.78
  Positive ≥5 mm, n (%) 18 (12) 9 (8)  
   TST+ median induration, mm (IQR) 16 (13–21) 13 (12–15) 0.19
  Negative, n (%) 125 (83) 88 (85)  
  Did not return, n (%) 6 (4) 6 (6)  
 QGIT     0.86
  Positive, n (%) 42 (28) 29 (28)  
   QGIT+ median IFN-γ, IU/ml (IQR) 3.22 (1.26–9.79) 1.84 (0.84–4.63) 0.11
  Negative, n (%) 103 (69) 70 (67)  
  Indeterminate, n (%) 4 (2) 4 (3)  

Definition of abbreviations: cART = combination antiretroviral therapy; IPT = isoniazid preventive therapy; IQR = interquartile range; LTBI = latent tuberculosis infection; MDR-TB = multidrug-resistant tuberculosis; NA = not applicable; QGIT = QuantiFERON TB Gold In-Tube test; TB = tuberculosis; TST = tuberculin skin test.

*

Statistically significant.