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. 2016 Mar 2;17(4):449–456. doi: 10.1080/15384047.2016.1156257

Figure 1.

Figure 1.

HBV activates STAT3 signaling which backs to promote HBV virus replication. (A) Western blotting analysis of STAT3 and p-STAT3 levels in HepG2.2.15 and HepG2 cells. (B) Western blotting analysis of STAT3 and p-STAT3 levels in HBV-stably transfected HepG2 and HL7702 cells. (C) Western blotting analysis of STAT3 and p-STAT3 levels in HepG2.2.15 cells incubated with 100 ng/mL IL-6. (D) After 6 h or 24 h, mRNA levels of HBx was analyzed by qRT-PCR in HepG2.2.15 cells incubated with 100 ng/mL IL-6. Data are expressed as the mean ± SEM from at least 3 separate experiments. *p < 0.05, **p < 0.01.