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AUClast +SE (in h x%ID/mg of tissue) for A549-WT and A549-DDP tumor models, after IV injection of NTG and TG nanoparticles at 3 mg/kg equivalent siRNA. n = 5 mice.
*p < 0.05; **p < 0.01; ***p < 0.001 (t-test TG vs NTG).
AUClast: Area under the concentration versus time curve until the last time point; DDP: Cisplatin; NTG: Nontargeted; TG: Targeted.
