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Comparison of reduction in the rate of moderate/severe exacerbations with BDP/FF versus formoterol in COPD patients. Adapted from FORWARD study: all patients (Wedzicha et al. 28) and data pooling from post hoc analysis on baseline blood eosinophil count (Siddiqui et al. 35). BDP/FF, beclometasone dipropionate/formoterol. 20% is the suggested minimal clinically important difference for exacerbations.47
