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. 2016 Jun 16;11(6):e0157877. doi: 10.1371/journal.pone.0157877

Table 1. Demographic characteristics and serum ICAM-1 and IL-6 levels among the participants according to their frailty status.

Variable Total Non-frail Pre-frail Frail p
Number 946 330 531 85
ICAM-1 (ng/ml)
mean±SD 276.4±96.2 263.3±88.9 276.7±91.5 325.3±131.2 <0.001
Median (IQR) 265.0(225.0–310.0) 255.0(210.0–300.0) 265.0(225.0–315.0) 285.0(250.0–360.0)
IL-6 levels (pg/ml) <0.001
mean±SD 4.0±6.2 3.8±7.2 3.9±5.1 5.7±8.2
Median (IQR) 2.5(2.0–4.0) 2.5(1.5–3.5) 2.5(2.0–4.0) 4.0(2.5–5.5)
Age, mean±SD (year) 65.5±9.4 63.2±8.2 65.5±9.4 74.4±7.9 <0.001
Sex, Men,rate (%) 520(100%) 51.8 40.5 47.1 0.005
Education, mean±SD (year) 7.4±4.9 8.7±5.0 7.2±4.6 4.1±4.4 <0.001
BMI, mean±SD (kg/m2) 24.8±3.5 24.8±3.4 24.9±3.4 24.6±4.0 0.737
Smoke, rate (%) <0.001
 Never 583(100%) 40.0 51.5 8.6
 Former 180(100%) 31.1 57.2 11.7
 Current 183(100%) 22.4 70.0 7.7
Number of chronic diseases, median(IQR) 1.0(0.0–2.0) 1.0(0.0–2.0) 1.0(0.0–2.0) 3.0(1.0–4.0) <0.001