Table 1. Demographic characteristics and serum ICAM-1 and IL-6 levels among the participants according to their frailty status.
Variable | Total | Non-frail | Pre-frail | Frail | p |
---|---|---|---|---|---|
Number | 946 | 330 | 531 | 85 | |
ICAM-1 (ng/ml) | |||||
mean±SD | 276.4±96.2 | 263.3±88.9 | 276.7±91.5 | 325.3±131.2 | <0.001 |
Median (IQR) | 265.0(225.0–310.0) | 255.0(210.0–300.0) | 265.0(225.0–315.0) | 285.0(250.0–360.0) | |
IL-6 levels (pg/ml) | <0.001 | ||||
mean±SD | 4.0±6.2 | 3.8±7.2 | 3.9±5.1 | 5.7±8.2 | |
Median (IQR) | 2.5(2.0–4.0) | 2.5(1.5–3.5) | 2.5(2.0–4.0) | 4.0(2.5–5.5) | |
Age, mean±SD (year) | 65.5±9.4 | 63.2±8.2 | 65.5±9.4 | 74.4±7.9 | <0.001 |
Sex, Men,rate (%) | 520(100%) | 51.8 | 40.5 | 47.1 | 0.005 |
Education, mean±SD (year) | 7.4±4.9 | 8.7±5.0 | 7.2±4.6 | 4.1±4.4 | <0.001 |
BMI, mean±SD (kg/m2) | 24.8±3.5 | 24.8±3.4 | 24.9±3.4 | 24.6±4.0 | 0.737 |
Smoke, rate (%) | <0.001 | ||||
Never | 583(100%) | 40.0 | 51.5 | 8.6 | |
Former | 180(100%) | 31.1 | 57.2 | 11.7 | |
Current | 183(100%) | 22.4 | 70.0 | 7.7 | |
Number of chronic diseases, median(IQR) | 1.0(0.0–2.0) | 1.0(0.0–2.0) | 1.0(0.0–2.0) | 3.0(1.0–4.0) | <0.001 |