Table 2. Multinomial logistic regression analysis to explore the association among the log ICAM-1 values, log IL-6 values, and frailty status using continuous measurements and serum ICAM-1 and I-6 level tertile categories.

	Model I		Model II		Model III
	Pre-frail	Frail	Pre-frail	Frail	Pre-frail	Frail
Using continuous measurements
Log (ICAM-1)
OR(95%CI)	1.06(0.91–1.23)	1.44(1.09–1.91)			1.05(0.90–1.22)	1.36(1.03–1.82)
Log (IL-6)
OR(95%CI)			1.08(0.94–1.25)	1.54(1.07–2.20)	1.08(0.93–1.25)	1.41(0.98–2.03)
Using tertiles
ICAM-1 tertiles
Bottom	reference	reference			reference	reference
Middle
OR(95%CI)	1.03(0.73–1.46)	2.57(1.14–5.80)			1.03(0.73–1.45)	2.57(1.13–5.82)
Top
OR(95%CI)	1.10(0.76–1.59)	2.43(1.08–5.44)			1.08(0.74–1.57)	2.21(0.97–4.98)
IL-6 tertiles
Bottom			reference	reference	reference	reference
Middle
OR(95%CI)			1.07(0.76–1.50)	1.28(0.60–2.74)	1.06(0.76–1.49)	1.26(0.58–2.71)
Top
OR(95%CI)			1.16(0.80–1.69)	2.34(1.14–4.76)	1.15(0.79–1.67)	2.28(1.10–4.89)

Adjusted for age, gender, education, smoke, chronic disease number, and BMI;