Table 1.
Frequencies of amino acids at site 173 of Env-gp70 differ in breakthrough infections in the presence of the DPB1*13 allele.
| Vaccine (n = 44)
|
Fisher’s P | Placebo (n = 66)
|
Fisher’s P | |||
|---|---|---|---|---|---|---|
| DPB1*13+ | DPB1*13− | DPB1*13+ | DPB1*13− | |||
| H173 | 8 | 15 | 0.004 | 9 | 19 | 0.57 |
| H173X* | 0 | 21 | — | 9 | 29 | — |
|
| ||||||
|
DPB1*13+ (n = 26)
|
DPB1*13− (n = 84)
|
|||||
| H173 | H173X | H173 | H173X | |||
|
| ||||||
| Vaccine | 8 | 0 | 0.02 | 15 | 19 | 1.00 |
| Placebo | 9 | 9 | — | 21 | 29 | — |
X designates amino acid residues other than histidine (H) at position 173.