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. 2016 Jun 16;11(6):e0157407. doi: 10.1371/journal.pone.0157407

Fig 6. Innate CD161+ T cell cytokine secretion and cytotoxic response in blood and mucosal tissues.

Fig 6

HMBPP-specific and fixed E.coli-induced secretion of IFN-γ (A) and Perforin (B) was analyzed in lymhocytes from PBMC, lung and colonic mucosa using enzyme-linked immunosorbent spot (ELISpot) assay. Enzyme-linked immunosorbent assay (ELISA) for TNF-α, IFN-γ, IL-17 and IL-13 in culture supernatants collected 16 hours following HMBPP (C) and E.coli (D) stimulation of lymhocytes from PBMC, lung and colonic mucosa. Data obtained from 6 rhesus macaques. Asterisks denote significant differences (p<0.05) calculated by the Wilcoxon matched-pairs signed rank test.