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. 2016 Jun 16;11(6):e0156801. doi: 10.1371/journal.pone.0156801

Table 1. Demographics and route to diagnosis in HCC patients.

A
Variable HCC n = 304
Sex/male (%) 235 (77)
Age 68 (17–98)
Male 68 (17–98)
Female 69 (33–88)
Aetiology/% (*)
Alcohol related liver disease 21.7 (37.5%)
Non alcohol related fatty liver disease 19.7 (26.3%)
Hepatitis C 13.8 (21.7%)
Hereditary haemochromatosis 2.6 (4.6%)
Hepatitis B 3.3 (4.3%)
B
Total HCC n = 304 100%
Index event triggering diagnosis
Screening 133 43.80%
Standard optimal () 90 29.6% (1.6%)
Suboptimal 25 8.20%
Detected incidentally out with screening (††) 14 (8) 4.6% (2.6%)
Detected only on transplant explants 4 1.30%
Symptomatic consistent with HCC 67 22.00%
Presentation (‡‡) 53 (4) 17.40%
Incidental finding on imaging 47 15.50%

Aetiology is given for the 5 most prevalent. Percentages apply for cases where only a single aetiology was defined; bracketed percentages refer to the total of cases where aetiological factor was either alone or as a cofactor. Other aetiologies were %; AIH 2.3 (2.3), PBC 3.0 (3.3), PSC 0 (0), Hepatic sarcoid 0.3 (0.3), Secondary haemochromatosis 0.3 (0.3), Confirmed non cirrhotic 1 (1), Cryptogenic cirrhosis 15.5. (% total of sole aetiology and as cofactor).

Median (range),

*Sole aetiology (total of sole and cofactor),

Optimal, but CT/MRI due to habitus,

††incidental at OLT assessment,

‡‡Representation to liver clinic.