Table 1. Demographics and route to diagnosis in HCC patients.
A | ||
Variable | HCC n = 304 | |
Sex/male (%) | 235 (77) | |
Age† | 68 (17–98) | |
Male | 68 (17–98) | |
Female | 69 (33–88) | |
Aetiology/% (*) | ||
Alcohol related liver disease | 21.7 (37.5%) | |
Non alcohol related fatty liver disease | 19.7 (26.3%) | |
Hepatitis C | 13.8 (21.7%) | |
Hereditary haemochromatosis | 2.6 (4.6%) | |
Hepatitis B | 3.3 (4.3%) | |
B | ||
Total HCC | n = 304 | 100% |
Index event triggering diagnosis | ||
Screening | 133 | 43.80% |
Standard optimal (‡) | 90 | 29.6% (1.6%) |
Suboptimal | 25 | 8.20% |
Detected incidentally out with screening (††) | 14 (8) | 4.6% (2.6%) |
Detected only on transplant explants | 4 | 1.30% |
Symptomatic consistent with HCC | 67 | 22.00% |
Presentation (‡‡) | 53 (4) | 17.40% |
Incidental finding on imaging | 47 | 15.50% |
Aetiology is given for the 5 most prevalent. Percentages apply for cases where only a single aetiology was defined; bracketed percentages refer to the total of cases where aetiological factor was either alone or as a cofactor. Other aetiologies were %; AIH 2.3 (2.3), PBC 3.0 (3.3), PSC 0 (0), Hepatic sarcoid 0.3 (0.3), Secondary haemochromatosis 0.3 (0.3), Confirmed non cirrhotic 1 (1), Cryptogenic cirrhosis 15.5. (% total of sole aetiology and as cofactor).
†Median (range),
*Sole aetiology (total of sole and cofactor),
‡Optimal, but CT/MRI due to habitus,
††incidental at OLT assessment,
‡‡Representation to liver clinic.