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. 2016 Jun 16;11(6):e0156639. doi: 10.1371/journal.pone.0156639

Fig 6. Overexpression of capsule reduces antibody binding to the surface of GAS.

Fig 6

Representative histograms showing the binding of anti-SV1 antibodies to (A) the invasive M1 GAS strain 5448, (B) the acapsular ΔhasA and (C) the capsule overexpressing 5448 AP. Binding and anti-M1 antibodies to the same strains is shown in panels D-F respectively. In all images the grey shaded histogram represents binding of sera from mice immunised with PBS to GAS cells and open black lined histograms represent anti-SV1 or anti-M1-protein antibody binding to GAS strains.