Table 2. Predictors of all-cause mortality in the study population of HF.

		Univariate model		Baseline model		Baseline model + CRP		Baseline model+ CRP + ST2
Variable		HR [95% CI]	p	HR [95% CI]	p	HR [95% CI]	p	HR [95% CI]	p
Age		1.048 [1.021–1.075]	< 0.001	1.03 [1.002–1.058]	0.037	1.03 [1.002–1.058]	0.032	1.039 [1.01–1.068]	0.008
Gender	M	1.209 [0.7–2.089]	0.496	1.341 [0.715–2.516]	0.361	1.44 [0.762–2.722]	0.261	1.391 [0.738–2.624]	0.308
Vascular risk factor		4.325 [1.356–13.798]	0.013	2.53 [0.736–8.695]	0.14	3.111 [0.893–10.836]	0.075	3.185 [0.905–11.211]	0.071
Pulmonary risk factor		0.951 [0.58–1.558]	0.841	1.199 [0.704–2.043]	0.504	1.371 [0.793–2.368]	0.259	1.419 [0.815–2.469]	0.216
Dyslipidemia		1.129 [0.689–1.852]	0.63	0.982 [0.555–1.737]	0.951	0.748 [0.41–1.364]	0.344	0.824 [0.45–1.51]	0.531
NYHA class		1.728 [1.258–2.374]	0.001	1.411 [0.983–2.023]	0.062	1.292 [0.904–1.846]	0.16	1.126 [0.763–1.661]	0.549
Ischemic cardiopathy		1.056 [0.644–1.731]	0.83	0.884 [0.494–1.581]	0.677	0.905 [0.508–1.612]	0.735	0.883 [0.495–1.575]	0.674
LVEF		0.989 [0.97–1.008]	0.247	0.999 [0.974–1.024]	0.919	0.998 [0.974–1.023]	0.886	0.994 [0.97–1.019]	0.652
Sodium		0.981 [0.923–1.042]	0.526	0.975 [0.914–1.042]	0.458	0.965 [0.905–1.03]	0.287	0.971 [0.912–1.034]	0.364
NT-proBNP (log 10)		3.046 [1.972–4.705]	< 0.001	2.654 [1.516–4.647]	0.001	2.453 [1.417–4.245]	0.001	1.762 [0.981–3.164]	0.058
Hs-cTnT (log 10)		1.669 [1.218–2.287]	0.001	0.865 [0.549–1.365]	0.534	0.793 [0.502–1.253]	0.32	0.742 [0.466–1.182]	0.208
CRP (log 10)		2.109 [1.44–3.089]	< 0.001			1.839 [1.179–2.867]	0.007	1.614 [1.031–2.527]	0.036
ST2 (log 10)		3.915 [2.31–6.635]	< 0.001					2.751 [1.205–6.28]	0.016

CI: confidence interval; COPD: Chronic obstructive pulmonary disease, NYHA: New York Heart Association, LVEF: left ventricular ejection fraction, eGFR CKD-EPI: estimated glomerular filtration rate Chronic Kidney Disease—Epidemiology Collaboration.