Fig. 1. Effects of mangiferin (MAN) on the viability of LNCaP prostate carcinoma cells. (A) Chemical structure of MAN. (B) LNCaP cells treated with the indicated concentrations of MAN or 20 ng/ml TNF-α in the presence or (C) absence of serum for 24 h. Cell viability was measured using an MTT assay after 24 h. (D) Total DNA was extracted from the treated cells, and a DNA fragmentation assay was performed on a 1.5% agarose gel. MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium briomide.
