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. Author manuscript; available in PMC: 2016 Jun 16.
Published in final edited form as: Annu Rev Anal Chem (Palo Alto Calif). 2016 Mar 30;9(1):95–115. doi: 10.1146/annurev-anchem-071015-041514

Figure 6.

Figure 6

In vivo detection of the conversion of pyruvate to lactate using hyperpolarized 13C magnetic resonance imaging (MRI). (a) Stack of MR spectra showing the time course of the decay of pyruvate and the buildup of lactate in the MR image of a rat. (b) 1H MR image of the rat showing the location of muscle. Temporal parametric maps of the biodistributions of pyruvate and lactate show the production of lactate in muscle. Reproduced with permission from Reference 98.