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. 2016 May 2;5(4):474–498. doi: 10.1002/wdev.233

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© 2016 The Authors. WIREs Developmental Biology published by Wiley Periodicals, Inc.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Terminal selector regulons. (a) Schematic illustration of terminal identity features that are controlled by terminal selector‐type transcription factors. These identity features are continuously expressed throughout the life of a neuron. (b) Three examples of terminal selector regulons. All genes shown here were shown to be direct targets of the indicated terminal selectors.7, 121, 138 In addition to the genes shown here, scores of additional genes have been identified as being expressed in the respective neuron types and containing binding sites for the respective regulators, but these additional genes have not been validated for terminal selector‐dependence.