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Doubling time and vincristine (VCR) sensitivity of KB3, RS4;11, and primary ALL cells. The values for doubling time represent mean ± S.D. (n=6), and IC50 values were derived from data in Fig. S1.
| Doubling Time (d) |
IC50 VCR (nM) |
|
|---|---|---|
| KB3 | 1.0 ± 0.1 | 2.10 ± 0.09 |
| RS4;11 | 1.5 ± 0.3 | 1.05 ± 0.24 |
| ALL-2 | 2.5 ± 0.5 | 3.90 ± 0.07 |
| ALL-5 | 2.8 ± 0.6 | 0.60 ± 0.07 |
