Extended Data Figure 2. PRDM14 and CBFA2T2 exhibit an overlapping and interdependent distribution on chromatin in NCCIT cells.
a, Heatmap depicting PRDM14, CBFA2T2, RING1B and SUZ12 read density across a 5kb window centered about the PRDM14 (top) or RING1B (bottom) SERs identified in NCCIT cells.
b, Representative genome browser tracks depicting SERs at the indicated genomic loci.
c, Gene Ontology analysis of PRDM14/CBFA2T2 common target genes.
d, Western blot analysis of PRDM14 and CBFA2T2 protein levels in knockdown experiments (Fig. 1d, 1e).