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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2015 Dec 22;8(4):619–630. doi: 10.1002/wnan.1386

Figure 3.

Figure 3

(A) A schematic illustration of Au-IONP-Affibody. (B) A TEM image of Au-IONP. (C) A high-angle annular dark field image of Au-IONP. The Au nanoparticles were shown as the bright dots. (D) In vivo PET imaging of A431 tumor-bearing mice acquired 24 h after the injection of 64Cu-NOTA-Au-IONP-Affibody. From left to right: targeted group and blocking group. (E) In vivo MR imaging of A431 tumor-bearing mice acquired 24 h after the injection of 64Cu-NOTA-Au-IONP-Affibody. Tumors were marked by yellow arrow-heads. Reprinted with permission from [43].