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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Crit Care Med. 2016 Jul;44(7):1267–1277. doi: 10.1097/CCM.0000000000001651

Table 1. Methodological characteristics of 425 studies measuring ICU survivor outcomes (1970 - 2013).

Cross-sectional studies* Cohort studies with 1 follow-up assessment* Cohort studies with >1 follow-up assessment* Randomized Controlled Trials
N=116 (27%) N=168 (39%) N=110 (26%) N=31 (7%)

Months from discharge to last assessment: median (IQR) 31 (18 - 52) 6 (6 - 12) 12 (12 - 12) 12 (5 - 12)
No. follow-up assessments: median (IQR) 2 (2 - 3) 1 (1 - 2)
No. participants assessed at last follow-up time: median (IQR) 65 (37 - 125) 107 (53 - 255) 80 (46 - 146) 87 (32 - 199)
Loss to follow-up reported§ 80 (69%) 129 (77%) 40 (36%) 20 (65%)
Loss to follow-up: median (IQR)§ 22% (11% - 38%) 22% (7% - 37%) 14% (2% - 25%) 13% (6% - 25%)
*

In cross-sectional studies, participants were defined as eligible at the time of assessment. In cohort studies, eligible patients were defined as patients eligible for a follow-up assessment at any point in the study.

Time from discharge to assessment was reported using available data (i.e. means, when mean not reported, we used medians or calculated a value based on range as follows: (maximum response time - minimum response time)/2), with 4 cross-sectional and 2 cohort studies with 1 follow-up assessment not reporting time to assessment.

Number of participants assessed was not reported for 7 (6%) cross-sectional studies, 8 (5%) cohort studies with 1 follow-up assessment, 14 (13%) cohort studies with ≥1 follow-up assessments, and 3 (10%) randomized clinical trials.

§

Patients known to be deceased at the time of assessment were not considered lost to follow-up.