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. 2016 Jun 17;7:238. doi: 10.3389/fimmu.2016.00238

Figure 4.

Figure 4

Gene interaction network and intensity plot of SDEGs associated with Il-17 in Mtb-infected mouse lungs with or without CC-11050 treatment. (A) Interaction of member genes involved in Il-17 expression/regulation. Solid lines represent direct connection, and broken lines indicate indirect link. Red color indicates upregulation, and green color depicts downregulation. (B) Intensity plot of SDEGs associated with Il-17 network. UT, untreated; CC, treated with CC-11050. Red color shows upregulation, and blue color denotes downregulation of gene expression. Scale bar ranges from +3 (red) to −3 (blue).