Table 2.
Factors associated with mortality or liver transplantations among patients with stable cirrhosis n (%)
| Survivors (n = 111) | Death/liver transplantation (n = 27) | P value | |
| Age (yr), mean ± SD | 54.33 ± 12.11 | 50.67 ± 13.91 | 0.173 |
| Male gender | 79 (71.2) | 18 (66.7) | 0.646 |
| Etiology of cirrhosis | |||
| Alcohol | 34 (30.6) | 8 (29.6) | 0.919 |
| Hepatitis C | 42 (37.8) | 8 (29.6) | 0.426 |
| Hepatitis B | 4 (3.6) | 2 (7.4) | 0.334 |
| Cryptogenic | 10 (9.0) | 4 (14.8) | 0.475 |
| Other | 21 (18.9) | 5 (18.5) | 0.962 |
| Previous hospitalization | 73 (65.8) | 24 (88.9) | 0.018 |
| Active alcoholism | 3 (2.7) | 2 (7.4) | 0.252 |
| Propranolol | 67 (60.4) | 20 (74.1) | 0.185 |
| PPI | 54 (48.6) | 15 (55.6) | 0.520 |
| Complication at evaluation | |||
| Ascites | 19 (17.1) | 9 (33.3) | 0.060 |
| Hepatic encephalopathy | 8 (7.2) | 6 (22.2) | 0.032 |
| Previous ascites | 47 (42.3) | 19 (70.4) | 0.009 |
| Laboratory data | |||
| Leucocyte count (× 109), median | 4.93 | 4.83 | 0.548 |
| Sodium (meq/L), median | 138.00 | 136.00 | 0.022 |
| Creatinine (mg/dL), median | 0.9 | 0.8 | 0.480 |
| INR, median | 1.16 | 1.27 | < 0.001 |
| Albumin (g/dL), mean ± SD | 3.52 ± 0.44 | 3.11 ± 0.39 | < 0.001 |
| CRP (mg/L), median | 3.5 | 4.51 | 0.014 |
| Total bilirubin (mg/dL), median | 0.9 | 1.8 | < 0.001 |
| IGFBP-3 (mcg/mL), median | 1.74 | 1.44 | 0.027 |
| Child-Pugh B/C | 27 (24.3) | 19 (70.4) | < 0.001 |
| MELD score, mean ± SD | 9.32 ± 1.97 | 11.98 ± 2.24 | < 0.001 |
PPI: Proton-pump inhibitors; INR: International normalized ratio; CRP: C-reactive protein; IGFBP-3: Insulin-like growth factor-binding protein 3; MELD: Model for end-stage liver disease.