Table 3.

Hazard ratios of rectal cancer in adulthood for birth weight at 2.5, 3.5 and 4.5 kilograms, from the restricted cubic spline model.^a

						Birth weight
			2.5 kg			3.5 kg		4.5 kg
Sex	N	Cases	Hazard ratio	95% confidence interval		Hazard ratio	95% confidence interval	Hazard ratio	95% confidence interval
Allb	193,306	961	0.92	0.76	1.12	1.00 (ref)		0.77	0.61	0.96
Menc	98,068	582	0.97	0.75	1.24	1.00 (ref)		0.80	0.61	1.05
Womenc	95,238	379	0.89	0.66	1.19	1.00 (ref)		0.73	0.50	1.07

^aTo facilitate the interpretation of the restricted cubic spline model, point estimates are presented for birth weight values of 2.5, 3.5, and 4.5 kg, with 3.5 kg as the reference.

^bStratified by sex and birth cohort.

^cStratified by birth cohort.