Figure 2. Sensory neuron MyD88 is not required for motor function, baseline pain and acute inflammatory pain.
(A–C) Baseline pain was intact in CKO mice. (A) Motor function, revealed by falling latency in Rotarod test. (B) Mechanical pain sensitivity, assessed by tail withdrawal threshold in Randall-Selitto test. (C) Heat pain in tail flick test. n = 9~11 mice/group. (D,E) Formalin-induced acute inflammatory pain is intact in WT and MyD88 CKO mice. (D) The total flinch and licking time and (E) the time course of 5% formalin-induced pain behavior. n = 6~8 mice/group.