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. 2016 Jun 17;6:28140. doi: 10.1038/srep28140

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Copyright © 2016, Macmillan Publishers Limited

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Expressions of IFN-γ (A), IP-10 (B), and MIG (C) were significantly increased in the eyes that were injected with rIL-12. However, the expressions of VEGFA (D) and FGF2 (E) are not significantly changed in the rIL-12 injected group. Double staining for CD31 (green) and CD4 or CD8 (red) in cryostat sections of OIR eyes that were injected with PBS or rIL-12. Some CD4+ (F) and CD8+ cells (G) infiltrated in the retina (arrowheads) of the rIL-12 injected group. ^**P < 0.01, ^*P < 0.05 compared to the controls that were injected with PBS (n = 4/group). Scale bars: 100 μm.