Figure 4.

Experimental setup [A] and the measurement protocol [B] of the study. [A] Parallel monitoring of breath VOCs by PTR-TOF-MS (1), lung function parameters and pET-CO₂ by means of spirometry and capnometry (2) and hemodynamic parameters such as SV = stroke volume, CO = cardiac output, PR = pulse rate and MAP = mean arterial pressure (3). [B] Schematic spirogram of the whole experiment during tidal breathing and FEV manoeuvre. Spirogram of FEV manoeuver: VC = vital capacity, VT = tidal volume, ERV = expiratory reserve volume, IRV = inspiratory reserve volume, IC = inspiratory capacity, RV = residual volume and TLC = total lung capacity.