FIGURE 7.

Impact of HCMV infection status on postvaccination NK cell responses. NK cell IFN-γ, CD107a, and CD25 responses are shown for 33 HCMV IgG-seronegative (open symbol) and 19 HCMV IgG-seropositive individuals (closed symbol) after stimulation with H1N1 virus alone (A–C), H1N1 in the presence of LCC (D–F), or HCC (G–I) before (0) or 2, 4, or 12 wk after vaccination. Bars represent mean values. Comparisons between HCMV⁻ and HCMV⁺ individuals were made using Mann–Whitney U tests. *p < 0.05, **p < 0.01, ***p < 0.001.