Figure 6.

Spatial learning measurements obtained using operant conditioning chambers. The spread of responses (A) is expressed as a proportion of the rates of nose pokes at each location and is fit to a Gaussian function for both the vehicle-treated (r² = 0.99) and carboplatin-treated (r² = 0.96) rats (F [2,64] = 4.339, p < 0.05, n = 7, vehicle versus carboplatin). The responses at the nontarget positions, 2 and 4 (B), overall rates of nose pokes (C), and rats’ weights during the testing phase (D) are also shown (*p < 0.05, n = 7 rats per group).