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. 2016 Jun 17;20:152. doi: 10.1186/s13054-016-1321-6

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© Lelubre et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — The decision to administer red blood cell transfusions (RBCT) should take into consideration the potential benefits and harms of this intervention, according to different haemoglobin (Hb) levels at which RBCT is initiated. In brain-injured patients, the RBCT strategy should be “restrictive” (if Hb is less than 7.0 g/dl) in awake and conscious patients. For poor-grade comatose patients, systemic (superior vena cava oxygen saturation (ScvO ₂) or high lactate levels) or cerebral triggers (jugular vein oxygen saturation (SvjO ₂) or brain tissue oxygen pressure (PbtO ₂)) could be used to guide RBC administration